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Tags: protamine, cardiac surgery, blood, hear
(View ID:529516)
protamine did not , Oh, I did not! Last night, the First Affiliated Hospital of Dalian Medical University, director of Surgery Bian Xiaoming telephone call to reporters, journalists suddenly remembered that in September last year, has been reported, the National protamine tight, when the city there are tensions, but the major The hospital said stock, did not affect the surgery.The day before his anxious voice, and one of the phone said that I did not, by by not, the Protamine the shortage has reached a very serious stage.
Below we look at what is the protamine protamine is a basic protein in fish (such as salmon, squat fish, herring, etc.) in the mature sperm nucleus as DNA binding The presence of nuclear protamine.Protamine was found in 1870 to between 1940 and 1960, formally used as antibacterial agENTs began to flourish.Protamine in the molecular composition and collagen not fundamentally different, are of different types of amino acids.The past two years into a new beauty products, has also been made of medical injection for bleeding caused by heparin overdose, and no other Drugs can be an alternative.Protamine is a basic protein of sulfate extracted from the fish fresh mature sperm for bleeding caused by heparin overdose, and no other drugs can replace.At present, technical terms, can only be extracted from the fish's sperm can not be chemically synthesized, restricting production.
can be seen from the above interpretation of the definition of protamine can not synthesize the production of the disappearance of its invENTory is normal. in September 2010, around the country have appeared protamine shortage.90% of cardiac Surgery, use of protamine sulfate injection, and this drug without any other Drugs can replace the shortage means that there are a large number of patiENTs with heart disease can not surgery. It is understood that the protamine sulfate injection is a Medicare drug, each priced at 11 yuan.The industry believes that many years of soaring prices, and protamine sulfate injection remains low, this may be one of the reasons for manufacturers willing to produce.Network data, there are three companies holding a production approval of protamine, the other two 23 years ago, has stopped production of this variety, the country still only the first biochemical one in Shanghai to supply, but is said to 2011 7 onwards to temporarily suspend production.The importance of the protamine of currENTly taken by the majority of cardiac Surgery, cardiopulmonary bypass technology, blood lead out will be solidified, the solidification of the blood back to the body will produce thrombosis need heparin to prevent blood clotting, the addition of heparin, blood diluted will lead to bleeding, finished surgery, use of protamine and heparin, the blood of the normal state.
If protamine is really a serious lack is bound to affect the treatmENT of heart disease.Of similar protamine shortage of low-cost Drugs is not the case, many life-saving drugs are facing the dilemma of protamine.
protamine, cardiac surgery, blood, heart, sperm, fish, patient, medicine, basic proteins, unwilling to
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